abject
Meaning: wretched, pitiful
Usage: After losing all her money, falling into a puddle, and breaking her ankle, Eloise was abject.
anguish
Meaning: extreme sadness, torment
Usage: Angelos suffered terrible anguish when he learned that Buffy had died while combating a strange mystical force of evil.
bereft
Meaning: devoid of, without
Usage: His family was bereft of food and shelter following the tornado.
dour
Meaning: stern, joyless
Usage: The children feared their dour neighbor because the old man would take their toys if he believed they were being too loud.
morose
Meaning: gloomy or sullen
Usage: Jason’s morose nature made him very unpleasant to talk to.